IDENTIFYING NETWORK MOTIFS THAT BUFFER FRONT-TO-BACK SIGNALING IN POLARIZED NEUTROPHILS

Neutrophil polarity relies on local, mutual inhibition to segregate incompatible signaling circuits to the leading and trailing edges.Mutual inhibition alone should lead to cells having strong fronts and weak backs or vice versa.However, analysis of cell-to-cell variation in human neutrophils revealed that back polarity remains consistent despite c

In the past decade, plug-in (hybrid) electric vehicles (PHEVs) have been widely caramilk latte proposed as a viable alternative to internal combustion vehicles to reduce fossil fuel emissions and dependence on petroleum.Off-peak vehicle charging is frequently proposed to reduce the stress on the electric power grid by shaping the load curve.Time of